In Fenton's reaction, the ferrous and/or ferric cation decomposes catalytically hydrogen peroxide to generate powerful oxidizing agents, capable of degrading a number of organic and inorganic substances.
What is Fenton reaction in human body?
The Fenton reaction produces the hydroxyl radical, which is a ROS that is detrimental to the human body. Understanding the spontaneity of the different nucleobases interacting with the hydroxyl radical to produce mutated bases can help in limiting the damage caused to DNA.
Is the Fenton reaction Bad?
The toxic metal ions can be harmful to the human body and cause diseases like Alzheimer's disease and cancer. The Fenton reaction produces the hydroxyl radical, which is a ROS that is detrimental to the human body.
Why does the Fenton reaction happen?
The Fenton reaction is possible because transition metals can exist in more than one oxidation state and their valence electrons may be unpaired, allowing them to participate in one-electron redox reactions.
How does Fenton reaction work?
The Fenton reaction describes the formation of hydroxide (OH−) and hydroxyl radical by a reaction between Iron (II) (Fe2+) and hydrogen peroxide (H2O2) [33], Haber–Weiss reaction is where hydroxyl and hydroxide ions are generated from the reaction of H2O2 and superoxide ion ( O 2 • − ) catalyzed by iron [34].
How do you stop a Fenton reaction?
- An excess of thiosulphate.
- DTPA which is much better than EDTA.
- Deferoxamine which is strong iron specific chelator.
- Catalase.
- methanol or ethanol is an efficient agent for scavenging hydroxyl radicals in the Fenton's process.
What does the Fenton reaction do?
Iron and hydrogen peroxide are capable of oxidizing a wide range of substrates and causing biological damage. The reaction, referred to as the Fenton reaction, is complex and capable of generating both hydroxyl radicals and higher oxidation states of the iron.
Why does Fenton reaction occur?
The Fenton reaction is possible because transition metals can exist in more than one oxidation state and their valence electrons may be unpaired, allowing them to participate in one-electron redox reactions. The Fenton reaction generates two types of oxidants, Type I and Type II.