Pluronic F68 is used in cell culture as a stabilizer of cell membranes protecting from membrane shearing and additionally acts as an anti-foaming agent.
What is Pluronic acid?
Pluronics® or poloxamers are tri-block copolymers of poly(ethylene oxidepoly(ethylene oxideThere is only a slight increase in electrical conductivity with PEG400 (lowest MW), from 0.1 to 0.24 S/cm, when PEG concentration is below 1 × 10−2 mol/L. However, a sharp increase is observed with increasing PEG concentrations and reach a maximum of 17.7 S/cm at 4.06 × 10−2 mol/L.https://www.sciencedirect.com › science › article › piiEffects of poly(ethylene glycol) on electrical conductivity of poly(3,4 ...) poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO) (Lippens et al., 2013). ... To overcome this problem, Pluronic is frequently crosslinked with another α-hydroxy or amino acid in order to alter the chemical structure of its depsipeptide unit.
What is Pluronic water?
Pluronic F-127 *10% solution in water* is a nonionic, surfactant polyol (molecular weight approximately 12,500 daltons) that has been found to facilitate the solubilization of water-insoluble dyes and other materials in physiological media.
What is Pluronic F68?
Gibco® Pluronic® F-68 is a non-ionic surfactant used to control shear forces in suspension cultures. Pluronic® F-68 can also be used to reduce foaming in stirred cultures and reduce cell attachment to glass. Pluronic® F-68 is provided at a concentration of 10% and effective at a working concentration of 0.1%.
Is Pluronic a poloxamer?
Let us mention that Pluronic is a poloxamer, i.e., an amphiphilic copolymer composed of a central hydrophobic chain of polyoxypropylene (poly-propylene oxide) flanked by two hydrophilic chains of polyoxyethylene (polyethylene oxidepolyethylene oxideThere is only a slight increase in electrical conductivity with PEG400 (lowest MW), from 0.1 to 0.24 S/cm, when PEG concentration is below 1 × 10−2 mol/L. However, a sharp increase is observed with increasing PEG concentrations and reach a maximum of 17.7 S/cm at 4.06 × 10−2 mol/L.https://www.sciencedirect.com › science › article › piiEffects of poly(ethylene glycol) on electrical conductivity of poly(3,4 ...).
What is poloxamer 188 used for?
Poloxamer 188 is a medication used to clean wounds. Poloxamer 188 (P188) is a nonionic block linear copolymer that exhibits rheologic, anti-thrombotic, anti-inflammatory, and cytoprotective activities in various tissue injury models 5.Dec 3, 2015
What is Pluronic used for?
In terms of applications, while Pluronics are known to inhibit surface–tissue adhesion for many cell types (Klouda and Mikos, 2008), they have been successfully used for scaffolding applications that involve hematopoietic stem cells (Higuchi et al., 2006) and lung tissue (Cortiella et al., 2006).