Page kidney or Page phenomenon results from external compression of the kidney by a chronic subcapsular hematoma. It is a rare, treatable cause of secondary hypertension mediated by activation of the renin-angiotensin-aldosterone system (RAAS).
How is Page kidney diagnosed?
The diagnosis of Page kidney depends on the presence of either a surrounding hematoma or an encasing fibrous pseudocapsule. CT abdomen is the preferred modality as it is noninvasive and can detect even very small hematomas [6]. MRI may be helpful in assessing the age of the hematomas and patency of renal blood vessels.
What is Goldblatt hypertension?
In 1934, pathologist Harry Goldblatt established the first animal model of hypertension. This model provided researchers with the tools to delineate the renin-angiotensin system of blood pressure control and, eventually, to design enzyme inhibitors for the treatment of chronic hypertension.
How is Page kidney treated?
Page kidney is defined as the external compression of the kidney, typically by a subcapsular hematoma, that leads to hypertension due to hypoperfusion and ischemia. The treatment options include medical anti-hypertensive treatment, percutaneous drainage, surgical decortication and nephrectomy.
What is one kidney Goldblatt hypertension?
In the second, one-clip one-kidney Goldblatt hypertension, the contralateral kidney is removed. In this case the pressure natriuresis can no longer occur, and sodium retention occurs. The ensuing expansion of plasma volume inhibits renin secretion, so that in this model the renin level is normal or low.
What causes renal artery stenosis?
The two main causes of renal artery stenosis include: Buildup on kidney (renal) arteries. Fats, cholesterol and other substances (plaque) can build up in and on your kidney artery walls (atherosclerosis).May 9, 2020
What is renovascular hypertension?
Renovascular hypertension is high blood pressurehigh blood pressureHypertension tends to run in families. Individuals whose parents have hypertension have an elevated risk of developing the condition, particularly if both parents are affected. However, the inheritance pattern is unknown. Rare, genetic forms of hypertension follow the inheritance pattern of the individual condition.https://medlineplus.gov › genetics › condition › hypertensionHypertension - Genetics - MedlinePlus due to narrowing of the arteries that carry blood to the kidneys. This condition is also called renal artery stenosis.
What is a page kidney?
Page kidney is defined as the external compression of the kidney, typically by a subcapsular hematoma, that leads to hypertension due to activation of the renin-angiotensinaldosterone (RAA) axis by hypoperfusion and microvascular ischemia of the kidney.
What causes renal hematoma?
[1] Subcapsular renal hematomas are usually related to kidney trauma and are well-known complications of ESWL. [2] The causes of spontaneous hematoma include tumors, vascular diseases, infections, cystic diseases, hydronephrosis, preeclampsia and blood dyscrasias.
Can a hematoma cause kidney failure?
It can cause hemorrhagic shock when the active bleeding fails to be prevented. Even when the active bleeding is controlled, the SRH will lead to high blood pressure and subsequent renal failure since the active subcapsular bleeding will accumulate around the kidney and compressed it for a substantial amount of time.
What is subcapsular renal hematoma?
A subcapsular perirenal hematoma is a form of perirenal hematoma where blood accumulates beneath the renal capsular margin.