Iron reduction therapy significantly reduced the median level of serum AFP from 13 to 7 ng/mL, ALT from 96 to 50 IU/L, gamma-glutamyl transpeptidase (GGT) from 55 to 28 IU/L, and ferritin from 191 to 10 ng/mL ( for each).
What is the treatment for AFP?
Certain types of liver cancer related to high AFP levels may be treated with targeted therapy. Targeted therapy uses drugs or other substances that attack specific cancer cells with less harm to normal cells. This therapy may be more effective and cause fewer side effects than traditional chemotherapy.26 Aug 2021
What can raise AFP levels?
High levels of AFP can be a sign of liver cancer or cancer of the ovaries or testicles, as well as noncancerous liver diseases such as cirrhosis and hepatitis.26 Aug 2021
Can AFP levels fluctuate?
Fluctuations in serum AFP levels within the normal range occur in patients during this follow-up period, causing anxiety about relapse. Patients frequently question the significance of an increase in AFP within normal levels and whether it predicts for relapse.24 Sept 2012
What can affect AFP results?
Your baby may make more AFP than normal, or you could be having twins (two babies make more AFP than one). Other things, including your race, weight, and having diabetes, can also affect your result.13 Nov 2021
What level of AFP indicates cancer?
An AFP level between 10 ng/mL to 20 ng/mL is normal for adults. An extremely high level of AFP in your blood—greater than 400 ng/mL—could be a sign of liver tumors. High levels of AFP may mean other cancers, including Hodgkin disease, lymphoma, and renal cell carcinoma (kidney cancer).
What can cause a false positive AFP test?
Around 50 percent of the tests are considered to be false-positive. That means that the test is falsely being reported as positive. False-positive results may be because the mother is carrying twins, inaccurate dates, a low birth weight infant, a large placenta or a sample that was contaminated.15 Jan 2017